Question: What Should You Avoid When Taking Methotrexate?

Can methotrexate cause weight gain?

Methotrexate was shown to cause a modest amount of weight gain over 6 months, in a study measuring weight changes in people with rheumatoid arthritis.

The patients who were most likely to gain weight when starting methotrexate, were patients who had recently lost weight due to rheumatoid arthritis..

Does methotrexate make you tired?

Methotrexate can lower your white blood count, which can make you more likely to get an infection. It can also cause hair loss and make you bruise more easily. Some people get headaches and fatigue for a day or two after taking methotrexate, which is usually taken by mouth once a week.

How bad is methotrexate for you?

Methotrexate may cause serious or life-threatening skin reactions. If you experience any of the following symptoms, call your doctor immediately: fever, rash, blisters, or peeling skin. Methotrexate may decrease the activity of your immune system, and you may develop serious infections.

Do you lose weight on methotrexate?

This medication is a disease-modifying antirheumatic drug. It can cause diarrhea, nausea, and an upset stomach, any of which may lead to weight loss. The study examined weight gain and weight loss in more than 30,000 people who were taking RA medication, such as methotrexate, prednisone, or leflunomide.

How can I boost my immune system while on methotrexate?

Taking folic acid You may be prescribed folic acid tablets while you’re taking methotrexate. This is a man-made version of vitamin B9 (also called folate). Folic acid helps protect the healthy cells in your body and reduces some of the side effects of methotrexate.

Does methotrexate shorten your life?

Methotrexate My Decrease Rate of Mortality in Rheumatoid Arthritis (RA) Numerous studies have shown that patients with RA have reduced life expectancy.

Is there an alternative to methotrexate?

In elderly patients with RA who are unable to tolerate methotrexate, the alternatives are hydroxychloroquine or sulfasalazine for mild-to-moderate disease and cyclosporin or leflunomide for severe disease, given in combination with low-dose oral corticosteroids.

How long do you stay on methotrexate?

Many patients with rheumatoid arthritis have stayed on this drug for 20 years or more.

Can I take vitamin D with methotrexate?

No interactions were found between methotrexate and Vitamin D3. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Can methotrexate cause vitamin D deficiency?

Methotrexate is a significant risk factor for suboptimal vitamin D status, therefore, patients on MTX therapy may require a correction of vitamin D supplementation to maintain optimal 25(OH) D levels.

Does methotrexate affect memory?

At 15 weeks of age (8 weeks after the last methotrexate dose) both spatial pattern memory and visual recognition memory were impaired. In addition, methotrexate-treated animals demonstrated impaired performance in the set-shifting assay, indicating decreased cognitive flexibility.

When should I take methotrexate morning or night?

“The most common side effects are fatigue a day or two after you take methotrexate, which is why I suggest taking it at night,” he says. “Also gastrointestinal issues.

Should I drink lots of water with methotrexate?

It is important to take methotrexate exactly as directed by your doctor. Take the dose with a glass of water while standing or sitting upright. Drink plenty of water (8 cups or 2,000 mL [2 litres]) on the day you take your methotrexate.

Can I take vitamin C while on methotrexate?

No interactions were found between methotrexate and Vitamin C.

What vitamins should I take with methotrexate?

Taking folic acid can help to make up for, or supplement, the folate that your body loses when you take methotrexate. Folic acid supplements, which are taken orally, can help decrease the side effects from folate deficiency.

What is the safest drug for rheumatoid arthritis?

Hydroxychloroquine. Hydroxychloroquine is an antimalarial drug which is relatively safe and well-tolerated agent for the treatment of rheumatoid arthritis. Chloroquine is another antimalarial agent that is also sometimes used.

Does methotrexate affect sleep?

Studies Show Link Between Inflammation and Sleep Disruption Another study, published in August 2017 in the journal NeuroImmunoModulation, concluded that inflammation influences sleep. Researchers revealed that treatment with methotrexate or Enbrel (etanercept) improved sleep quality.

What can you not take with methotrexate?

Top 10 List of Safety Tips for MethotrexateTopicsFast FactsPrescription medicines that should not be taken with methotrexateCheck with your doctor; some of the medicines that may be a problem include: acitretin, cyclosporine, sulfonamides, trimethoprim, vaccines, clozapine, carbamazepine15 more rows